Ingegneria tissutale come nuovo approccio al trattamento delle patologie valvolari cardiache

Abstract

Vascular cells have been successfully utilized for tissue engineering in human cardiovascular structures, such as heart valves. The present study evaluates saphenous vein-derived myofibroblasts as an alternative, easy-to-access cell source for human cardiovascular tissue engineering. Immunohistochemistry was performed to characterize cell phenotipe. In conclusion, saphenous vein myofibroblasts cultured,showed excellent in vitro tissue generation. Therefore, the easy-to-access vein cells represent a promising alternative cell source for cardiovascular tissue engineering.