Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.advisorGnudi, Giacomo-
dc.contributor.advisorGrolli, Stefano-
dc.contributor.authorGrassi, Lucia-
dc.description.abstractFibrosi epatica nel cane, cause, diagnosi, terapia tradizionale, approccio nutrizionale e terapia con staminali mesenchimali (MSCs)it
dc.description.abstractIn the context of Small Animal Veterinary Medicine, canine hepatic fibrosis represents an important clinical issue due to its challenging nature. There are several different histological aspects attributable to the various conditions included under the category of chronic hepatitis (CH). A better understanding of the pathological mechanisms underlying hepatic fibrosis could lead to the development of less invasive diagnostic strategies; unfortunately, there is still much to achieve to replace the practice of the histological assessment of liver biopsy specimen, which for years has been considered the gold standard. Conventional therapy seems to provide good results against Copper-associated Liver Diseases, but there is still no standard for Idiopathic Chronic Hepatitis, which represents one of the most common Liver diseases featuring hepatic fibrosis in dogs. The use of anti-fibrotic drugs has been examined in order to establish better results without resorting to a specific therapy, but no satisfactory solutions have been detected so far. The Mesenchymal Stem Cells (MSCs) therapeutic potential in preventing and treating hepatic fibrosis has been widely investigated due to the variety of their biological properties. According to some scientific studies performed on dogs as animal models, the administration route might be able to influence the therapeutic outcomes, making more invasive approaches necessary. More studies have to be performed in order to assess the durability of the beneficial effects of MSCs administration for canine hepatic fibrosis treatmentit
dc.publisherUniversità di Parma. Dipartimento di Scienze Medico-Veterinarieit
dc.relation.ispartofseriesLaurea Magistrale a ciclo unico in Scienze Medico-Veterinarieit
dc.rights© Lucia Grassi, 2020it
dc.subjectHepatic fibrosisit
dc.subjectMesenchymal Stem Cells (MSCs)it
dc.subjectLiver Diseasesit
dc.titleFibrosi epatica nel cane: stato dell'arte e nuove prospettiveit
dc.title.alternativeCanine hepatic fibrosis: state of the art and new perspectivesit
dc.typeBachelor thesisit
Appears in Collections:Scienze medico-veterinarie

Files in This Item:
File Description SizeFormat 
Tesi Lucia Grassi.pdfElaborato definitivo Tesi di laurea2.62 MBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.